Description: Description:Sickle Cell Anemia is a common genetic disease that causes long rods in red blood cells, giving them a "sickled" appearance. These cells get stuck in small capillaries of the blood stream leading to oxygen deprivation that causes pain and organ damage. Sickle Cell Anemia is caused by a single point mutation in the hemoglobin gene that results in a faulty protein. In this experiment, your students will investigate the restriction enzyme that discriminates between HbA (normal) and HbS (disease) genes and perform a simulated test on a patient.Features• Discover how a single nucleotide mutation can profoundly affect a person’s health• Explore Mendelian genetics and the molecule methods used to identify sickle cell disease• Perform agarose gel electrophoresis to separate differently-sized DNA molecules• Load, run, analyze, and size control samples and samples from a family of three to identify mutations in their hemoglobin genesIncludes:Instructions, Ready-to-Load QuickStrip™ DNA Samples, UltraSpec-Agarose™, Electrophoresis Buffer (50X), Practice Gel Loading Solution, FlashBlue™ DNA Stain
Price: 123.49 USD
Location: Camarillo, California
End Time: 2024-11-17T08:17:07.000Z
Shipping Cost: 0 USD
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Item Specifics
All returns accepted: ReturnsNotAccepted
Brand: Edvotek
MPN: BLG116
Type: Sickle Cell Gene Detection
Intended Use/Discipline: Biological Laboratory